Patients hospitalized with active tuberculosis and covid-19 coinfection: a matched case-control from the brazilian covid-19 registry
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Universidade Federal de Minas Gerais
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Artigo de periódico
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Membros da banca
Resumo
Although control of Covid-19 has improved, the virus continues to cause , such as tuberculosis, that is still endemic in many countries, representing a scenario of coinfection. To compare Covid-19 clinical manifestations and outcomes between patients with active tuberculosis infection and matched controls. This is a matched case-control study based on data from the Brazilian Covid-19 Registry, in hospitalized patients aged 18 or over with laboratory confirmed Covid-19 from March 1, 2020, to March 31, 2022. Cases were patients with tuberculosis and controls were Covid-19 patients without tuberculosis. From 13,636 Covid-19, 36 also had active tuberculosis (0.0026%). Pulmonary fibrosis (5.6% vs 0.0%), illicit drug abuse (30.6% vs 3.0%), alcoholism (33.3% vs 11.9%) and smoking (50.0% vs 9.7%) were more common among patients with tuberculosis. They also had a higher frequency of nausea and vomiting (25.0% vs 10.4%). There were no significant differences in in-hospital mortality, mechanical ventilation, need for dialysis and ICU stay. Patients with TB infection presented a higher frequency of pulmonary fibrosis, abuse of illicit drugs, alcoholism, current smoking, symptoms of nausea and vomiting. The outcomes were similar between them.
Abstract
Assunto
Covid-19, Hospitalization, Infectious Disease Medicine, Prognosis, Tuberculosis
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Covid-19, Hospitalization, Infectious diseases, Prognosis, Tuberculosis
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https://www.scielo.br/j/aabc/a/LZkLNbdr8tdrzkVBfpYTJWx/?lang=en