Patients hospitalized with active tuberculosis and covid-19 coinfection: a matched case-control from the brazilian covid-19 registry

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dc.creatorRafael Lima Rodrigues de Carvalho
dc.creatorFernando Anschau
dc.creatorJose Miguel Chatkin
dc.creatorKaren Brasil Ruschel
dc.creatorMarcelo Carneiro
dc.creatorNeimy Ramos de Oliveira
dc.creatorPedro Gibson Paráiso
dc.creatorRubia Laura Oliveira Aguiar
dc.creatorGenna Maíra Santos Grizende
dc.creatorMilena Soriano Marcolino
dc.creatorGabriela Genta Aguiar
dc.creatorJessica Fernandes Benavides Moreira
dc.creatorDaniella Nunes Pereira
dc.creatorValeria Maria Augusto
dc.creatorAlexandre Vargas Schwarzbold
dc.creatorCarolina Cunha Matos
dc.creatorDanyelle Romana Alves Rios
dc.creatorFelicio Roberto Costa
dc.date.accessioned2025-07-24T17:32:58Z
dc.date.accessioned2025-09-09T00:59:52Z
dc.date.available2025-07-24T17:32:58Z
dc.date.issued2024
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.1590/0001-3765202420230791
dc.identifier.issn16782690
dc.identifier.urihttps://hdl.handle.net/1843/83817
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofAnais da Academia Brasileira de Ciências
dc.rightsAcesso Aberto
dc.subjectCovid-19
dc.subjectHospitalization
dc.subjectInfectious Disease Medicine
dc.subjectPrognosis
dc.subjectTuberculosis
dc.subject.otherCovid-19
dc.subject.otherHospitalization
dc.subject.otherInfectious diseases
dc.subject.otherPrognosis
dc.subject.otherTuberculosis
dc.titlePatients hospitalized with active tuberculosis and covid-19 coinfection: a matched case-control from the brazilian covid-19 registry
dc.typeArtigo de periódico
local.citation.epage10
local.citation.issue1
local.citation.spage1
local.citation.volume96
local.description.resumoAlthough control of Covid-19 has improved, the virus continues to cause , such as tuberculosis, that is still endemic in many countries, representing a scenario of coinfection. To compare Covid-19 clinical manifestations and outcomes between patients with active tuberculosis infection and matched controls. This is a matched case-control study based on data from the Brazilian Covid-19 Registry, in hospitalized patients aged 18 or over with laboratory confirmed Covid-19 from March 1, 2020, to March 31, 2022. Cases were patients with tuberculosis and controls were Covid-19 patients without tuberculosis. From 13,636 Covid-19, 36 also had active tuberculosis (0.0026%). Pulmonary fibrosis (5.6% vs 0.0%), illicit drug abuse (30.6% vs 3.0%), alcoholism (33.3% vs 11.9%) and smoking (50.0% vs 9.7%) were more common among patients with tuberculosis. They also had a higher frequency of nausea and vomiting (25.0% vs 10.4%). There were no significant differences in in-hospital mortality, mechanical ventilation, need for dialysis and ICU stay. Patients with TB infection presented a higher frequency of pulmonary fibrosis, abuse of illicit drugs, alcoholism, current smoking, symptoms of nausea and vomiting. The outcomes were similar between them.
local.publisher.countryBrasil
local.publisher.departmentMED - DEPARTAMENTO DE CLÍNICA MÉDICA
local.publisher.initialsUFMG
local.url.externahttps://www.scielo.br/j/aabc/a/LZkLNbdr8tdrzkVBfpYTJWx/?lang=en

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