Antibacterial-containing dental adhesives effects on oral pathogens and on Streptococcus mutans biofilm: current perspective
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Universidade Federal de Minas Gerais
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Artigo de periódico
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Purpose: To describe the literature findings regarding commercially available antibacterial-containing
dental adhesives and the futures perspectives of this field. Results: High-risk caries patients could yield benefits from
restorative materials containing antibacterial properties in order to reduce the recurrent caries formation. Dental
adhesives with antibacterial agents may reduce restoration replacement, as recurrent caries is still one of the major
reasons for replacing a resin restoration. Literature results of three commercially available adhesives: Gluma 2Bond,
Clearfil SE Protect and Peak Universal Bond, containing glutaraldehyde, MDPB and chlorhexidine, respectively
indicates that Clearfil SE Protect seems to have better results against oral pathogens and on Streptococcus mutans
biofilm. Besides the promising findings, clinical studies are still necessary in order to validate the clinical efficacy when
exposed to a more complex environment and the long-term effect of either commercially available materials,
experimental antibacterial monomers or antibacterial incorporations. As a suggestion of this article and according to the
current scientific trends in this specific field, future directions should focus on restorative materials with therapeutic
components targeting the virulence factors of cariogenic biofilm with minimal toxicity and side effects, and long-term
action. (Am J Dent 2018;31:(Sp Is B):37B-41B).
CLINICAL SIGNIFICANCE: Antibacterial-containing dental adhesives may have therapeutic effects, working as an
additional source to reduce recurrent caries development in patients with high-risk of caries, and consequently the
reduction in restoration replacements
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Anti-bacterial agents, Dental caries, Dental restoration repair
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http://www.amjdent.com/previousarticles.htm