Antibacterial-containing dental adhesives effects on oral pathogens and on Streptococcus mutans biofilm: current perspective

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dc.creatorCarolina Bosso André
dc.creatorDaniel Chan
dc.creatorMarcelo Giannini
dc.date.accessioned2022-08-29T18:35:03Z
dc.date.accessioned2025-09-09T00:02:21Z
dc.date.available2022-08-29T18:35:03Z
dc.date.issued2018-11
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
dc.description.sponsorshipFAPESP - Fundação de Amparo à Pesquisa do Estado de São Paulo
dc.format.mimetypepdf
dc.identifier.issn08948275
dc.identifier.urihttps://hdl.handle.net/1843/44677
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofAmerican Journal of Dentistry
dc.rightsAcesso Aberto
dc.subjectAnti-bacterial agents
dc.subjectDental caries
dc.subjectDental restoration repair
dc.titleAntibacterial-containing dental adhesives effects on oral pathogens and on Streptococcus mutans biofilm: current perspective
dc.typeArtigo de periódico
local.citation.epage41B
local.citation.issueSpecial Issue B
local.citation.spage37B
local.citation.volume31
local.description.resumoPurpose: To describe the literature findings regarding commercially available antibacterial-containing dental adhesives and the futures perspectives of this field. Results: High-risk caries patients could yield benefits from restorative materials containing antibacterial properties in order to reduce the recurrent caries formation. Dental adhesives with antibacterial agents may reduce restoration replacement, as recurrent caries is still one of the major reasons for replacing a resin restoration. Literature results of three commercially available adhesives: Gluma 2Bond, Clearfil SE Protect and Peak Universal Bond, containing glutaraldehyde, MDPB and chlorhexidine, respectively indicates that Clearfil SE Protect seems to have better results against oral pathogens and on Streptococcus mutans biofilm. Besides the promising findings, clinical studies are still necessary in order to validate the clinical efficacy when exposed to a more complex environment and the long-term effect of either commercially available materials, experimental antibacterial monomers or antibacterial incorporations. As a suggestion of this article and according to the current scientific trends in this specific field, future directions should focus on restorative materials with therapeutic components targeting the virulence factors of cariogenic biofilm with minimal toxicity and side effects, and long-term action. (Am J Dent 2018;31:(Sp Is B):37B-41B). CLINICAL SIGNIFICANCE: Antibacterial-containing dental adhesives may have therapeutic effects, working as an additional source to reduce recurrent caries development in patients with high-risk of caries, and consequently the reduction in restoration replacements
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE ODONTOLOGIA RESTAURADORA
local.publisher.initialsUFMG
local.url.externahttp://www.amjdent.com/previousarticles.htm

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