Avaliação olfatória após acesso endonasal endoscópico a tumores hipofisários com e sem confecção de retalho nasosseptal

Abstract

Introduction: The advancement of endoscopic endonasal surgery for sellar tumors has allowed for access into previously visually inaccessible areas. However, this approach may have otorhinolaryngological morbidities, such as cerebrospinal fluid leak and olfactory dysfunction. Objectives: to evaluate the impact on olfaction in patients submitted to nasal endoscopic surgery in the sellar region with an without nasoseptal flap reconstruction using objective testing in a prospective study conducted at a tertiary care hospital. Methods: Patients were divided into two groups. Group 1 underwent bilateral transseptal access, and Group 2 underwent transseptal/transnasal approach with a pedicled nasoseptal flap reconstruction. Olfactory outcomes were assessed using the Connecticut Chemosensory Clinical Research Center test preoperatively, at 3-6 months postoperatively, and 6 months postoperatively. Results: of the 36 patients who completed the study, 22 were assigned to Group 1 and 14 to Group 2. No significant change in olfactory function was observed in either group across any of the time points (p> 0.05). Among all participants, one experienced postoperative cerebrospinal fluid leak (7%). Conclusion: This study demonstrated that endoscopic endonasal surgery for sellar tumors, resulted in no statistically significant differences in olfaction, measured by objective testing.