Clinicopathologic features associated with recurrence of the odontogenic keratocyst: a cohort retrospective analysis
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Universidade Federal de Minas Gerais
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Artigo de periódico
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Objective: The aim of this study was to evaluate the influence of clinical, radiographic, surgical and histopathologic parameters in the recurrence of disease in a series of odontogenic keratocysts (OKCs). Study design: The sample comprised 24 sporadic OKC lesions from 24 patients. All patients had no previous treatment history and were treated by the same surgeon using a uniform treatment protocol (enucleation with peripheral ostectomy preceded or not preceded by decompression). Results: Fourteen lesions (58.4%) were first submitted to decompression procedure. Eight patients (33%) developed recurrent lesions, with a mean follow-up time of 60.5 months (standard deviation [SD] = 31.3) and a mean disease-free interval for recurrent lesions of 19 months (SD = 4.9). Recurrence was significantly associated with poor clinical response to decompression (P = .027), remaining tooth with radiographic evidence of insinuation of the lesion between the dental roots (P = .009), and the presence of budding of the basal cells layer together with epithelial islands in the fibrous capsule (P = .019). Conclusions: Clinical, radiographic and histopathologic parameters may affect the relapse rate of OKCs and should individually guide treatment choice.
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Odontogenic cysts, Recurrence, Radiography, Therapeutics, Wounds and injuries, Tooth root
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https://www.sciencedirect.com/science/article/pii/S2212440316000171?via%3Dihub