Clinicopathologic features associated with recurrence of the odontogenic keratocyst: a cohort retrospective analysis

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dc.creatorJoanna Farias da Cunha
dc.creatorCarolina Cavalieri Gomes
dc.creatorRicardo Alves de Mesquita
dc.creatorEugênio Marcos Andrade Goulart
dc.creatorWagner Henriques de Castro
dc.creatorRicardo Santiago Gomez
dc.date.accessioned2025-05-23T19:08:48Z
dc.date.accessioned2025-09-08T23:31:42Z
dc.date.available2025-05-23T19:08:48Z
dc.date.issued2016-06
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.1016/j.oooo.2016.01.015
dc.identifier.issn2212-4411
dc.identifier.urihttps://hdl.handle.net/1843/82483
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofOral surgery oral medicine oral pathology oral radiology
dc.rightsAcesso Restrito
dc.subjectOdontogenic cysts
dc.subjectRecurrence
dc.subjectRadiography
dc.subjectTherapeutics
dc.subjectWounds and injuries
dc.subjectTooth root
dc.titleClinicopathologic features associated with recurrence of the odontogenic keratocyst: a cohort retrospective analysis
dc.typeArtigo de periódico
local.citation.epage635
local.citation.issue6
local.citation.spage629
local.citation.volume121
local.description.resumoObjective: The aim of this study was to evaluate the influence of clinical, radiographic, surgical and histopathologic parameters in the recurrence of disease in a series of odontogenic keratocysts (OKCs). Study design: The sample comprised 24 sporadic OKC lesions from 24 patients. All patients had no previous treatment history and were treated by the same surgeon using a uniform treatment protocol (enucleation with peripheral ostectomy preceded or not preceded by decompression). Results: Fourteen lesions (58.4%) were first submitted to decompression procedure. Eight patients (33%) developed recurrent lesions, with a mean follow-up time of 60.5 months (standard deviation [SD] = 31.3) and a mean disease-free interval for recurrent lesions of 19 months (SD = 4.9). Recurrence was significantly associated with poor clinical response to decompression (P = .027), remaining tooth with radiographic evidence of insinuation of the lesion between the dental roots (P = .009), and the presence of budding of the basal cells layer together with epithelial islands in the fibrous capsule (P = .019). Conclusions: Clinical, radiographic and histopathologic parameters may affect the relapse rate of OKCs and should individually guide treatment choice.
local.identifier.orcidhttps://orcid.org/0000-0003-1580-4995
local.identifier.orcidhttps://orcid.org/0000-0003-3207-4007
local.identifier.orcidhttps://orcid.org/0000-0003-2745-2878
local.identifier.orcidhttps://orcid.org/0000-0001-8770-8009
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICA
local.publisher.departmentICB - DEPARTAMENTO DE MORFOLOGIA
local.publisher.departmentICB - DEPARTAMENTO DE PATOLOGIA
local.publisher.initialsUFMG
local.url.externahttps://www.sciencedirect.com/science/article/pii/S2212440316000171?via%3Dihub

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