1. Repositório Institucional da UFMG
  2. Publicações Científicas e Culturais
  3. Artigo de Periódico
Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/44446
Full metadata record
DC FieldValueLanguage
dc.creatorRenato Sobral Monteiro Juniorpt_BR
dc.creatorPauline Maillotpt_BR
dc.creatorValeska Gatica-Rojaspt_BR
dc.creatorWaldney Roberto de Matos e Ávilapt_BR
dc.creatorAlfredo Maurício Batista de Paulapt_BR
dc.creatorAndré Luiz Sena Guimarãespt_BR
dc.creatorSergio Henrique Sousa Santospt_BR
dc.creatorCamila Castelo Branco Pupept_BR
dc.creatorAndréa Camaz Deslandespt_BR
dc.date.accessioned2022-08-22T15:10:08Z-
dc.date.available2022-08-22T15:10:08Z-
dc.date.issued2019-02-
dc.citation.volume123pt_BR
dc.citation.spage63pt_BR
dc.citation.epage66pt_BR
dc.identifier.doihttps://doi.org/10.1016/j.mehy.2018.12.013pt_BR
dc.identifier.issn0306-9877pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/44446-
dc.description.resumoFor many years lactate was seen as a metabolite from glucose metabolism. However, since the last century researchers have shown that this molecule has an important role on liver, muscle, and brain metabolism. Lactate traffics along whole body mediating many biological processes depending on specific situations. For example, glucose is the main substrate used during exercise but lactate released by striated skeletal muscle is used by own muscle as secondary fuel. On the other hand, neuronal firing in the brain is almost totally lactate-dependent. In addition, lactate has an important role on BDNF-mediated neuroplasticity. As this molecule has a pleiotropic role in the body, it was called as “lactormone” in 2009. Here we show basic concepts on peripheral and central metabolism and discuss neurobiological pathways of lactate, including an alternative hypothesis on lactate released during exercise.pt_BR
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológicopt_BR
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Geraispt_BR
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superiorpt_BR
dc.description.sponsorshipFAPERJ - Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiropt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentICA - INSTITUTO DE CIÊNCIAS AGRÁRIASpt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofMedical Hypothesespt_BR
dc.rightsAcesso Abertopt_BR
dc.subject.otherLactatospt_BR
dc.subject.otherÁcido pirúvicopt_BR
dc.subject.otherExercícios físicospt_BR
dc.subject.otherNeuroplasticidadept_BR
dc.subject.otherGlicosept_BR
dc.subject.otherNeurociênciaspt_BR
dc.titleIs the “lactormone” a key-factor for exercise-related neuroplasticity? A hypothesis based on an alternative lactate neurobiological pathwaypt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.sciencedirect.com/science/article/pii/S0306987718310946?via%3Dihubpt_BR
Appears in Collections:Artigo de Periódico

Files in This Item:
File Description SizeFormat 
Is the lactormone a key-factor for exercise-related neuroplasticity.pdf724.38 kBAdobe PDFView/Open
Show simple item record


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.