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http://hdl.handle.net/1843/53603| Type: | Artigo de Periódico |
| Title: | Biomechanical study of the effect of platelet rich plasma on the treatment of medial collateral ligament lesion in rabbits |
| Authors: | Eduardo Louzada da Costa Luiz Eduardo Moreira Teixeira Bruno Jannotti Pádua Ivana Duval Araújo Leonardo de Souza Vasconcellos Luide Scalioni Borges Dias |
| Abstract: | Purpose: To evaluate the use of platelet-rich plasma in the early stages of healing of traumatic injury of the medial collateral ligament in the knee of rabbits. Methods: Thirty rabbits were subjected to surgical lesion of the medial collateral ligament. Of these, 16 were treated with platelet-rich plasma and 14 with saline (control). After 3 and 6 weeks of treatment, 50% of the animals from each group were sacrificed, and biomechanical tests were performed on the injured ligament to compare the tensile strength between the two groups. Results: Platelet-rich plasma significantly increased the tensile strength of the ligament in the groups treated after3 and 6 weeks. In the group treated with platelet-rich plasma vs. saline, the tensile strength values were 3192.5 ± 189.7 g/f vs. 2851.1 ± 193.1 g/f at3 weeks (p =0.005) and 5915.6 ± 832.0 g/f vs. 4187.6 ± 512.9 g/f at 6 weeks (p = 0.0001).Conclusion: The use of platelet-rich plasma at the injury site accelerated ligament healing in an animal model, demonstrated by an increase in the tensile strength of the medial collateral ligament. |
| Subject: | Ligamento Colateral Médio do Joelho Traumatismos do Joelho Joelho Ratos |
| language: | eng |
| metadata.dc.publisher.country: | Brasil |
| Publisher: | Universidade Federal de Minas Gerais |
| Publisher Initials: | UFMG |
| metadata.dc.publisher.department: | MED - DEPARTAMENTO DE APARELHO LOCOMOTOR MED - DEPARTAMENTO DE CIRURGIA MED - DEPARTAMENTO DE PROPEDÊUTICA COMPLEMENTAR |
| Rights: | Acesso Aberto |
| metadata.dc.identifier.doi: | 10.1590/s0102-865020170100000004 |
| URI: | http://hdl.handle.net/1843/53603 |
| Issue Date: | 2017 |
| metadata.dc.url.externa: | https://www.scielo.br/j/acb/a/QTZ9zhn8pDs9dgS9NJsjcYj/?lang=en |
| metadata.dc.relation.ispartof: | Acta Cirúrgica Brasileira |
| Appears in Collections: | Artigo de Periódico |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Biomechanical study of the effect of platelet rich plasma on the treatment of medial collateral ligament pdfa.pdf | 6.51 MB | Adobe PDF | View/Open |
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