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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/57646
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dc.creatorRicardo Adriano Dorledo de Fariapt_BR
dc.creatorManuel Noel Paul Georges Houmardpt_BR
dc.creatorVerônica Aparecida Martins do Rosáriopt_BR
dc.creatorVanessa de Freitas Cunha Linspt_BR
dc.creatorLuiz Guilherme Dias Heneinept_BR
dc.creatorTulio Matenciopt_BR
dc.date.accessioned2023-08-09T13:16:51Z-
dc.date.available2023-08-09T13:16:51Z-
dc.date.issued2019-
dc.citation.volume33pt_BR
dc.citation.issue4pt_BR
dc.citation.spage437pt_BR
dc.citation.epage447pt_BR
dc.identifier.doihttps://doi.org/10.15255/CABEQ.2019.1699pt_BR
dc.identifier.issn1846-5153pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/57646-
dc.description.resumoGiven the importance of the transducer elements in the performance of sensors for various applications, as well as the growing search for devices that are capable of providing the response in shorter time, in this work, titanium dioxide was examined as a candidate for application in an electrochemical biosensor. A TiO2 coating deposited by sol-gel method on a silicon wafer was obtained with an anatase crystalline structure, as an n-type semiconductor with donor density equal to 2.954 · 1017 cm–3. Its surface was functionalized to be tested as a biosensor to detect snake venom of the Bothrops genera, and each step of the functionalization was investigated using Electrochemical Impedance Spectroscopy (EIS) and Cyclic voltammetry. Despite being less sensitive than the reference method ELISA, the TiO2-based biosensor was also capable of detecting the analyte of interest at 20 μg mL–1, revealing an increase in its leakage resistance and phase shift after incubation in this solution. Furthermore, the total time for carrying out the biodetection with the TiO2-coated device (41.24 ± 0.05 min) was estimated to be approximately 80 % shorter than that required by the labelled standard assay, which indicates that TiO2 is a promising electrochemical transducer for biosensing applications.pt_BR
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológicopt_BR
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Geraispt_BR
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superiorpt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentENG - DEPARTAMENTO DE ENGENHARIA QUÍMICApt_BR
dc.publisher.departmentICX - DEPARTAMENTO DE QUÍMICApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofChemical and Biochemical Engineering Quarterlypt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectTitanium dioxidept_BR
dc.subjectBiosensorpt_BR
dc.subjectTransducerpt_BR
dc.subjectElectrochemical impedance spectroscopypt_BR
dc.subject.otherEletroquímicapt_BR
dc.subject.otherEspectroscopia de impedânciapt_BR
dc.subject.otherDióxido de titâniopt_BR
dc.subject.otherBiossensorespt_BR
dc.subject.otherDetectores eletroquímicospt_BR
dc.subject.otherVoltametriapt_BR
dc.subject.otherCobra venenosa — Venenopt_BR
dc.titleTiO2 sol-gel coating as a transducer substrate for impedimetric immunosensorspt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttp://silverstripe.fkit.hr/cabeq/past-issues/article/1699pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-7025-7042pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-1543-5416pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-6357-9553pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-0707-2691pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-5660-8125pt_BR
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