1. Repositório Institucional da UFMG
  2. Publicações Científicas e Culturais
  3. Artigo de Periódico
Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/60195
Full metadata record
DC FieldValueLanguage
dc.creatorSafa Abbespt_BR
dc.creatorSung Vo Duypt_BR
dc.creatorGabriel Munozpt_BR
dc.creatorQuoc Tuc Dinhpt_BR
dc.creatorDana F. Simonpt_BR
dc.creatorBarry Huskpt_BR
dc.creatorHelen M. Baulchpt_BR
dc.creatorBrigitte Vinçon-Leitept_BR
dc.creatorNathalie Fortinpt_BR
dc.creatorCharles W. Greerpt_BR
dc.creatorMegan L. Larsenpt_BR
dc.creatorJason J. Venkiteswaranpt_BR
dc.creatorFelipe Fernando Martínez Jerónimopt_BR
dc.creatorAlessandra Gianipt_BR
dc.creatorChris D. Lowept_BR
dc.creatorNicolas Tromaspt_BR
dc.creatorSébastien Sauvépt_BR
dc.date.accessioned2023-10-27T21:07:54Z-
dc.date.available2023-10-27T21:07:54Z-
dc.date.issued2022-
dc.citation.volume14pt_BR
dc.citation.issue4pt_BR
dc.identifier.doihttps://doi.org/10.3390/toxins14040251pt_BR
dc.identifier.issn2072-6651pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/60195-
dc.description.resumoThe neurotoxic alkaloid β-N-methyl-amino-l-alanine (BMAA) and related isomers, including N-(2-aminoethyl glycine) (AEG), β-amino-N-methyl alanine (BAMA), and 2,4-diaminobutyric acid (DAB), have been reported previously in cyanobacterial samples. However, there are conflicting reports regarding their occurrence in surface waters. In this study, we evaluated the impact of amending lake water samples with trichloroacetic acid (0.1 M TCA) on the detection of BMAA isomers, compared with pre-existing protocols. A sensitive instrumental method was enlisted for the survey, with limits of detection in the range of 5–10 ng L−1. Higher detection rates and significantly greater levels (paired Wilcoxon’s signed-rank tests, p < 0.001) of BMAA isomers were observed in TCA-amended samples (method B) compared to samples without TCA (method A). The overall range of B/A ratios was 0.67–8.25 for AEG (up to +725%) and 0.69–15.5 for DAB (up to +1450%), with absolute concentration increases in TCA-amended samples of up to +15,000 ng L−1 for AEG and +650 ng L−1 for DAB. We also documented the trends in the occurrence of BMAA isomers for a large breadth of field-collected lakes from Brazil, Canada, France, Mexico, and the United Kingdom. Data gathered during this overarching campaign (overall, n = 390 within 45 lake sampling sites) indicated frequent detections of AEG and DAB isomers, with detection rates of 30% and 43% and maximum levels of 19,000 ng L−1 and 1100 ng L−1, respectively. In contrast, BAMA was found in less than 8% of the water samples, and BMAA was not found in any sample. These results support the analyses of free-living cyanobacteria, wherein BMAA was often reported at concentrations of 2–4 orders of magnitude lower than AEG and DAB. Seasonal measurements conducted at two bloom-impacted lakes indicated limited correlations of BMAA isomers with total microcystins or chlorophyll-a, which deserves further investigation.pt_BR
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Geraispt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentICB - DEPARTAMENTO DE BOTÂNICApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofToxinspt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectLake waterpt_BR
dc.subjectβ-N-methyl-amino-l-alanine (BMAA)pt_BR
dc.subject2,4-diaminobutyric acid (DAB)pt_BR
dc.subjectN-(2- aminoethyl) glycine (AEG)pt_BR
dc.subjectTrichloroacetic acid (TCA)pt_BR
dc.subjectTemporal trendspt_BR
dc.subject.otherLagospt_BR
dc.subject.otherCianobactériaspt_BR
dc.subject.otherToxinas de cianobactériaspt_BR
dc.titleOccurrence of BMAA isomers in bloom-impacted lakes and reservoirs of Brazil, Canada, France, Mexico, and the United Kingdompt_BR
dc.title.alternativeOcorrência de isômeros BMAA em lagos e reservatórios afetados pelo florescimento do Brasil, Canadá, França, México e Reino Unidopt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.mdpi.com/2072-6651/14/4/251pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-3725-2482pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-9018-4998pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-0190-0209pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-1484-9817pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-2524-8534pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-8584-1690pt_BR
Appears in Collections:Artigo de Periódico

Files in This Item:
File Description SizeFormat 
Occurrence of BMAA isomers in bloom-impacted lakes and reservoirs of Brazil, Canada, France, Mexico, and the United Kingdom.pdf7.31 MBAdobe PDFView/Open
Show simple item record


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.