Please use this identifier to cite or link to this item:
http://hdl.handle.net/1843/63873
Type: | Artigo de Periódico |
Title: | Direct sequential C-H iodination/organoyl-thiolation for the benzenoid A-ring modification of quinonoid deactivated systems: a new protocol for potent trypanocidal quinones |
Authors: | Guilherme Augusto de Melo Jardim Willian Xerxes Coelho Oliveira Rossimiriam Pereira de Freitas Rubem Figueiredo Sadok Menna Barreto Thaissa Lúcio Silva Marilia Oliveira Fonseca Goulart Eufrânio Nunes da Silva Júnior |
Abstract: | We report a sequential C–H iodination/organoyl-thiolation of naphthoquinones and their relevant trypanocidal activity. Under a combination of AgSR with a copper source, sulfur-substituted benzenoid quinones were prepared in high yields (generally >90%). This provides an efficient and general method for preparing A-ring modified naphthoquinoidal systems, recognized as a challenge in quinone chemistry. |
Subject: | Química orgânica Quinona |
language: | eng |
metadata.dc.publisher.country: | Brasil |
Publisher: | Universidade Federal de Minas Gerais |
Publisher Initials: | UFMG |
metadata.dc.publisher.department: | ICX - DEPARTAMENTO DE QUÍMICA |
Rights: | Acesso Restrito |
metadata.dc.identifier.doi: | https://doi.org/10.1039/C8OB00196K |
URI: | http://hdl.handle.net/1843/63873 |
Issue Date: | 2018 |
metadata.dc.url.externa: | https://pubs.rsc.org/en/content/articlelanding/2018/ob/c8ob00196k |
metadata.dc.relation.ispartof: | Organic & Biomolecular Chemistry |
Appears in Collections: | Artigo de Periódico |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.